Verbatim response from Perplexity
If you want a full-picture yearly bloodwork set and you’re otherwise generally healthy, the most common core tests are CBC, CMP, lipid panel, and diabetes screening with either HbA1c or fasting glucose; many clinicians also add TSH depending on age, symptoms, and risk factors.[1][3][5][7]
A practical yearly panel usually looks like this:
- Complete Blood Count (CBC) — looks at red blood cells, white blood cells, hemoglobin, hematocrit, and platelets; it helps screen for anemia, infection, and some blood disorders.[1][3][5]
- Comprehensive Metabolic Panel (CMP) — checks liver enzymes, kidney function, electrolytes, glucose, protein, albumin, and related markers; it gives a broad view of liver/kidney status and hydration/electrolyte balance.[1][3][7]
- Lipid panel — measures total cholesterol, LDL, HDL, and triglycerides to assess cardiovascular risk.[3][6][7]
- HbA1c — estimates your average blood sugar over the past 2–3 months and is used for screening prediabetes/diabetes.[3][7]
- Fasting glucose — another standard blood sugar screen often included in annual panels or paired with HbA1c.[2][4][7]
- TSH (thyroid-stimulating hormone) — commonly included in “annual checkup” panels, especially if you have fatigue, weight changes, constipation, palpitations, or a thyroid history.[3][7][13]
If you want a slightly more conservative “routine annual” set, one source describes CBC + chemistry panel/metabolic panel + urinalysis as the common yearly basics, with other tests added based on individual health needs.[5]
Tests that are not automatically yearly for everyone but are often reasonable depending on your situation include vitamin D, iron/ferritin, PSA, and sex-specific screening tests such as Pap/HPV or mammography, which are typically governed by age and screening guidelines rather than done universally as yearly bloodwork.[2][13]
If you want, I can turn this into a recommended yearly lab checklist by age/sex/risk level and separate what’s truly routine from what’s optional.