Verbatim response from Claude
Weight Loss on GLP-1 Medications
Typical Results
- Average loss: 15-20% of body weight over 12-18 months with the strongest options
- Most people lose 1-2 lbs per week initially, slowing over time
- Results vary significantly based on diet, activity, and individual response
Specific Medications (Fastest to Moderate)
Strongest options:
- Tirzepatide (Zepbound/Mounjaro) – up to 20-22% body weight loss in trials; currently the most effective
- Semaglutide (Wegovy/Ozempic) – approximately 15% body weight loss on average
Milder options:
- Liraglutide (Saxenda) – around 5-8% weight loss
Is It Sustainable? Honestly, It's Complicated
⚠️ The catch: Studies show most people regain significant weight within 1-2 years of stopping the medication
For sustainability, consider:
- Using the medication window to build lasting habits
- Working with services like Calibrate or Found that pair medication with lifestyle coaching
- Planning with your doctor about long-term use
Bottom Line
These drugs work remarkably well while taking them, but they're increasingly viewed as long-term or lifelong treatment, similar to blood pressure medication.
Would you like specifics on cost or access options?