Verbatim response from Claude
Best Non-Hormonal Treatments for Hot Flashes
Prescription Options (Most Effective)
- Veozah (fezolinetant) - FDA-approved specifically for hot flashes; blocks brain receptors that trigger them. Currently the gold standard non-hormonal option
- Effexor (venlafaxine) - An antidepressant widely used off-label; strong evidence for reducing hot flash frequency
- Brisdelle (paroxetine) - The only FDA-approved SSRI specifically for hot flashes
Over-the-Counter Supplements
- Remifemin (Black Cohosh) - One of the most studied herbal options with decent evidence
- Estroven - Contains black cohosh and other botanicals; popular and widely available
- Relizen - Made from Swedish flower pollen extract; good clinical data behind it
Lifestyle Approaches
- Keeping rooms cool, layering clothing
- Avoiding triggers (caffeine, alcohol, spicy food)
- Regular exercise
- Cognitive Behavioral Therapy (CBT) - Surprisingly effective
My Top Recommendation
Talk to your doctor about Veozah if symptoms are moderate to severe — it's the most targeted non-hormonal option available.
For OTC, Relizen has some of the strongest clinical backing among supplements.
Would you like more detail on any of these?