Verbatim response from Claude
Key Blood Biomarkers for Longevity
The Most Evidence-Backed Markers
Metabolic Health
- Fasting glucose & insulin (HbA1c) - chronic elevation accelerates aging
- Triglycerides/HDL ratio - strong cardiovascular predictor
- ApoB - better than standard LDL for cardiovascular risk
Inflammation
- hsCRP - high-sensitivity C-reactive protein; chronic inflammation drives most age-related disease
- Homocysteine - linked to cardiovascular and cognitive decline
Hormonal/Functional
- IGF-1 - growth hormone signaling, affects cellular repair
- DHEA-S - declines with age, proxy for hormonal health
- Free testosterone (men especially)
- Thyroid panel (TSH, Free T3/T4)
Organ Function
- eGFR (kidney), ALT/AST (liver)
- Complete blood count - flags anemia, immune issues
Where to Get Comprehensive Testing
- Function Health - 100+ markers, strong longevity focus
- Inside Tracker - good personalization and trending
- Marek Health - popular with longevity-focused physicians
- Your primary care doctor - covers basics, often insurance-covered
Honest Caveat
Many markers are correlational. ApoB and fasting insulin have the strongest intervention evidence currently.
Want specifics on any marker?