Verbatim response from Perplexity
If drugstore acne products aren’t working, the next step is to see a dermatologist or primary care clinician for prescription treatment. Adult acne that is deep, painful, or leaving scars is less likely to clear with over-the-counter products alone.[1][5]
What to do next:
- Make an appointment soon if you have moderate or severe acne, painful bumps, or scarring, or if OTC treatment has not helped after about 6–8 weeks to 2–3 months.[1][5][7]
- Don’t keep adding more products every few days; use one acne treatment consistently as directed before deciding it failed.[1][7]
- Ask about prescription options such as:
- Topical retinoids like prescription tretinoin or adapalene-style retinoid therapy.[5][6]
- Benzoyl peroxide + topical antibiotic combinations, since topical antibiotics should not be used alone.[6]
- Azelaic acid for inflammatory acne or if irritation is an issue.[5][6]
- Oral antibiotics for a limited time if acne is more inflammatory.[5][6]
- Hormonal treatment such as spironolactone or a combined oral contraceptive if your acne flares with hormones.[5][6]
- Isotretinoin if acne is severe, scarring, or not responding to other treatment.[6]
While waiting for the visit, the most evidence-backed OTC routine is:
- Benzoyl peroxide and/or adapalene 0.1% for acne-prone areas, not just spot treatment.[1][7]
- A noncomedogenic moisturizer to reduce irritation.[4][7]
- Gentle cleansing and avoiding harsh scrubs or aggressive exfoliation.[6][7]
If you tell me:
- where your acne is located,
- whether it’s mostly whiteheads/blackheads or deep cysts/painful bumps,
- and whether you’re pregnant or trying to conceive,
I can help you narrow down what treatment class is most likely to be prescribed.