Verbatim response from Perplexity
If you want a practical yearly blood-test baseline, the most common core set is CBC, CMP, lipid panel, and HbA1c; TSH is often added when there are thyroid symptoms or risk factors.[1][4][6][10]
A good way to think about it is:
- CBC (complete blood count) — checks for anemia, infection, inflammation, and some blood disorders.[1][4][8][10]
- CMP (comprehensive metabolic panel) — gives information about kidney function, liver function, electrolytes, and glucose.[1][4][6][8]
- Lipid panel — measures cholesterol and triglycerides to estimate cardiovascular risk.[1][4][7][8]
- HbA1c — shows average blood sugar over the past 2–3 months and helps screen for prediabetes/diabetes.[1][4][8]
- TSH — screens thyroid function, especially if you have fatigue, weight changes, constipation, palpitations, or a family history of thyroid disease.[1][4]
What makes sense beyond that depends on your age, sex, family history, medications, and symptoms. For example, some sources note that routine annual bloodwork is not strictly required for every healthy adult, and some screening tests are recommended less often unless you have risk factors.[7] The American Heart Association guidance cited by WebMD says a lipid screening may be done every 4–6 years in lower-risk adults, while diabetes screening becomes more important with age and risk factors.[7]
If you want a more complete yearly checkup, you might discuss adding:
- Vitamin B12 or iron studies if you have fatigue, anemia risk, or dietary restrictions.[5]
- Vitamin D if you have low sun exposure, bone concerns, or known deficiency.[3][5]
- PSA for prostate cancer screening if you’re in the age/risk group where it’s appropriate.[4]
- Hepatitis C screening at least once for adults, per CDC guidance cited by WebMD.[7]
A sensible “ask your doctor” list for many adults is:
- CBC
- CMP
- Lipid panel
- HbA1c
- TSH if indicated
- Plus any targeted tests based on your personal risks
If you tell me your age, sex, and any conditions or family history you have, I can suggest a more tailored yearly lab list.