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I have adult acne that drugstore products cannot fix. What should I do?

PerplexitydiscoveryCollected Jun 21, 2026, 09:34 UTC

Verbatim response from Perplexity

If drugstore acne products are not fixing your adult acne, the next step is to see a dermatologist rather than cycling through more over-the-counter products. Large, painful, deep pimples, acne that scars, or acne that has not improved after several weeks to a few months of consistent OTC use should be evaluated professionally.[3][6]

A dermatologist can match treatment to the type of acne you have and may prescribe:

  • Topical retinoids such as tretinoin or adapalene to unclog pores and speed cell turnover.[2][4][7]
  • Benzoyl peroxide or topical antibiotics like clindamycin, usually paired with benzoyl peroxide to reduce resistance.[2][7]
  • Oral antibiotics for more inflammatory acne.[2][6][7]
  • Hormonal treatments such as birth control pills or spironolactone if breakouts are hormonally driven.[2][7][8]
  • Isotretinoin for severe, persistent, or scarring acne that has not responded to other treatments.[2][7]

While you wait for an appointment, keep your routine simple:

  • Use a gentle cleanser and a non-comedogenic moisturizer.[1][7]
  • Use one active acne treatment at a time and give it 6 to 8 weeks to work.[3]
  • Avoid picking, harsh scrubs, and over-layering strong actives, which can worsen irritation.[1][7]

If you want a practical OTC option to try before or alongside a visit, dermatology sources most often recommend adapalene, benzoyl peroxide, and sometimes salicylic acid or azelaic acid for mild-to-moderate acne, but persistent adult acne often needs prescription treatment.[1][3][5][7]

If you tell me whether your acne is mostly deep painful bumps, whiteheads/blackheads, jawline flares, or scarring, I can help you narrow down the most likely next treatment to ask a dermatologist about.

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