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What does GLP-1 medication cost per month without insurance?

PerplexitypricingCollected Jun 27, 2026, 12:53 UTC

Verbatim response from Perplexity

GLP-1 medications for self-pay patients (without insurance) typically cost $149 to $499 per month, depending on the specific drug, dosage, and whether it is an injection or oral pill [1][5].

Key Cost Breakdown by Medication (Self-Pay Prices):

MedicationFormPrice Range (Self-Pay)Notes
Wegovy (semaglutide)Injection$149 – $199$149/month for 1.5 & 4 mg doses (through April 2026); 4 mg rises to $199/month after [1]
WegovyOral Pill$149 – $299Cash price ranges from $149 to $299/month depending on dosage [1]
Zepbound (tirzepatide)Injection$299 – $449$299 for 2.5 mg; $449 for higher doses (LillyDirect self-pay prices) [1][2]
Ozempic (semaglutide)Injection$199 – $499Introductory $199/month for first 2 fills; standard $349/month; $499 for 2 mg dose [3][5]
OzempicOral Pill$149Available starting at $149/month with GoodRx [3]
Liraglutide (generic)Injection$221Lowest price with discount coupon (SingleCare) [1]
Compounded SemaglutideInjection$141 – $199Via online planners (e.g. OnlineSemaglutide.org 6-month plan) [4]

Important Context:

  • List Prices Without Discounts: The standard list price for a month’s supply of a GLP-1 drug can range from $936 to $1,349 if insurance does not cover it and no self-pay program is used [1].
  • Self-Pay Programs: Many manufacturers (e.g., Novo Nordisk, Eli Lilly) now offer self-pay programs that significantly lower costs to the ranges listed above ($149–$499) [1][5].
  • Starter Doses: Lower-priced starter doses (e.g., 2.5 mg Zepbound at $299) are often available to reduce initial costs [1][2].
  • Oral Options: New FDA-approved daily pills (like oral Wegovy and Ozempic) are generally cheaper, often starting at $149/month for self-pay patients [1][3].

For the most affordable option, compounded semaglutide via online programs can cost as low as $141/month with a 6-month commitment [4], while Wegovy injections in self-pay programs are the lowest-priced branded option at $149/month [1].

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