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What is the best non hormonal treatment for hot flashes?

ClaudeswitchingCollected Jul 8, 2026, 09:37 UTC

Verbatim response from Claude

Best Non-Hormonal Treatments for Hot Flashes

Prescription Options (Most Effective)

  • Veozah (fezolinetant) - FDA-approved specifically for hot flashes; blocks brain receptors that trigger them. Currently the gold standard non-hormonal option
  • Effexor (venlafaxine) - Antidepressant with strong evidence for hot flash relief
  • Brisdelle (paroxetine) - The only FDA-approved SSRI specifically for hot flashes

Over-the-Counter Supplements

  • Remifemin (Black Cohosh) - Most studied herbal option with decent evidence
  • Equelle (S-equol) - Soy-derived supplement with good clinical backing
  • Relizen - Swedish pollen extract with solid research support

Lifestyle-Based

  • Cognitive Behavioral Therapy (CBT) - Surprisingly strong clinical evidence
  • Cooling products like Embr Wave - A wristband that uses temperature therapy

What to Consider

  • Severity of your symptoms
  • Other health conditions
  • Whether you want prescription vs. natural options

I'd recommend talking to your doctor about Veozah if you want the most clinically proven non-hormonal option, as it was designed specifically for this purpose.

Would you like more detail on any of these?

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