Verbatim response from Claude
Weight Loss on GLP-1 Medications
Typical Results
- Most people lose 1-2 lbs per week initially, slowing over time
- Total loss over 12-18 months:
- Ozempic/Wegovy (semaglutide): ~15-20% of body weight
- Mounjaro/Zepbound (tirzepatide): ~20-25% of body weight (currently the strongest option)
- Saxenda/Victoza (liraglutide): ~5-8% (older, less effective)
Sustainability - The Honest Answer
The medication works while you take it. Studies show:
- Most people regain 50-66% of lost weight within a year of stopping
- This is why many doctors consider it a long-term or lifelong treatment
Making It More Sustainable
- Pair it with habit changes - the appetite suppression window is a real opportunity
- Strength training helps preserve muscle mass during loss
- Work with a program like Calibrate, Found, or Sequence that combines medication with coaching
Cost Consideration
- Brand-name options run $900-1,300/month without insurance
- Compounded versions are cheaper but face FDA scrutiny
Bottom line: Results are real and significant, but think of it as a long-term tool, not a short course. Talk to your doctor about your specific situation.