How much does Zepbound cost monthly without insurance, and are the vials cheaper than pens?

Zepbound Pricing (Without Insurance)

Autoinjector Pens (standard retail):

• Starting doses (2.5mg, 5mg): ~$1,060/month
• Higher doses (10mg, 12.5mg, 15mg): ~$1,060/month
• Eli Lilly has standardized pricing across doses

Vials (Self-Pay Program): Eli Lilly launched vials specifically for cash-pay patients at significantly lower prices:

• 2.5mg and 5mg vials: ~$399/month
• 7.5mg and 10mg vials: ~$549/month

So yes, vials are substantially cheaper — roughly $500-$660 less per month than the pens.

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Ways to Reduce Costs Further

• Eli Lilly's savings card can bring costs down to ~$25/month if you have commercial insurance
• Lilly Direct is the official program to purchase vials directly
• GoodRx occasionally offers discounts worth checking
• Some compounding pharmacies have offered tirzepatide at lower prices, though the FDA has taken steps to restrict this

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I'd recommend checking LillyDirect.com directly for the most current vial pricing, as these figures can change. Always verify with your prescriber that vials are appropriate for your situation.