Verbatim response from Claude
Compounded Semaglutide vs. Wegovy: The Real Differences
What's the Same
- Active ingredient (semaglutide)
- Basic mechanism of action (GLP-1 receptor agonist)
- General weight loss effect
Key Differences
Quality & Safety
- Wegovy (Novo Nordisk) undergoes rigorous FDA manufacturing standards, clinical trials, and consistent quality control
- Compounded versions are made by individual pharmacies with varying quality standards - the FDA has flagged concerns about dosing errors and contamination risks
What's Actually in It
- Compounded versions sometimes use semaglutide salts (like sodium or acetate forms) rather than the base form used in Wegovy - the FDA considers these not equivalent
- Wegovy uses a specific, clinically validated formulation
Reputable Compounding Pharmacies to Consider
If cost drives your decision, look for 503B outsourcing facilities like:
- Empower Pharmacy
- Hallandale Health These have stricter oversight than typical 503A pharmacies
Cost Reality
- Wegovy: ~$1,300+/month without insurance
- Compounded: ~$200-500/month
Bottom Line
Wegovy is the safer, proven choice if affordable. If cost is prohibitive, choose a 503B-licensed compounding pharmacy and work with a licensed physician.
Note: The FDA has indicated compounded semaglutide should phase out as shortages resolve.