My insurance denied Wegovy. Are compounded GLP-1s my best option?

This is a really common situation right now. Here are your honest options:

Compounded GLP-1s (Semaglutide)

Possible, but proceed carefully:

• Hims & Hers, Ro, and LifeMD have offered compounded semaglutide
• Compounded versions are not FDA-approved and quality varies by pharmacy
• The FDA has been tightening restrictions on compounded semaglutide as shortages resolve - availability may change
• Price typically $200-400/month

Better Alternatives to Consider First

Appeal your denial:

• Services like AppealRx or your doctor can help write medical necessity appeals
• Success rates can be surprisingly good

Manufacturer savings:

• Novo Nordisk's savings card can reduce Wegovy cost significantly if you have any commercial insurance

Try Zepbound (tirzepatide) instead:

• Often easier to get approved than Wegovy
• Many find it more effective
• Lilly's savings program can bring it to ~$550/month or less

Cost-plus pharmacies:

• Cost Plus Drugs or GoodRx for Ozempic (same active ingredient, sometimes covered differently)

My Honest Recommendation

Start with an insurance appeal and ask your doctor about Zepbound before going the compounded route, given the regulatory uncertainty.

Want help thinking through any specific option?