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What is the best non hormonal treatment for hot flashes?

ClaudeswitchingCollected Aug 7, 2026, 12:15 UTC

Verbatim response from Claude

Best Non-Hormonal Treatments for Hot Flashes

Prescription Options

  • Veozah (fezolinetant) - FDA-approved specifically for hot flashes; targets brain receptors that trigger them. Very effective and relatively new.
  • Brisdelle (paroxetine 7.5mg) - The only FDA-approved SSRI for hot flashes
  • Effexor (venlafaxine) - Widely used off-label with good evidence

Supplements (OTC)

  • Remifemin - Black cohosh supplement with the most research support
  • Equelle - Contains S-equol (soy-derived) with solid clinical evidence
  • Amberen - Popular menopause supplement with some supporting studies

Lifestyle/Devices

  • Embr Wave - A wristband that uses temperature therapy to reduce hot flash discomfort
  • Chill Factor cooling towels or a Dyson fan for nighttime relief

Mind-Body

  • Cognitive Behavioral Therapy (CBT) - Strong evidence; apps like Woebot can help
  • Hypnotherapy - Surprisingly good clinical evidence

Important Notes

  • Veozah is currently considered the most effective non-hormonal prescription option
  • Always consult your doctor, especially if you have a history of breast cancer or liver issues

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