Verbatim response from Claude
BHRT Delivery Methods: A Practical Comparison
Pellets
Best for: Consistent, hands-off hormone delivery (3-6 months)
- Pros: Steady hormone levels, no daily effort, good for testosterone in women
- Cons: Irreversible once inserted, can cause overfill, minor procedure required
- Providers: BioTE Medical (largest pellet network), EvexiPEL, SottoPelle – all work through certified physician networks
Creams/Gels
Best for: Flexible dosing, easy adjustments
- Pros: Easily adjusted, topical application, good estrogen/progesterone options
- Cons: Transfer risk to partners/children, absorption varies
- Providers: Winona, Midi Health, Gennev (telehealth), compounding pharmacies like Belmar Pharma or Empower Pharmacy
Patches
Best for: Reliable estrogen delivery with strong safety data
- Pros: Consistent levels, bypasses liver, well-studied
- Cons: Skin irritation, adhesion issues, less customizable
- Brands: Vivelle-Dot, Climara, Minivelle (FDA-approved options)
Quick Recommendation
- Patches have the strongest conventional safety data
- Telehealth platforms like Midi or Winona offer convenient access to multiple delivery forms
- Always work with a licensed provider who monitors bloodwork regularly
Would you like more detail on cost or any specific option?