Verbatim response from Claude
Zepbound vs Wegovy: Quick Comparison
Which Works Better?
Zepbound (tirzepatide) generally wins on weight loss results:
- Average weight loss in trials: ~20-22% of body weight
- Targets two hormones (GIP + GLP-1)
Wegovy (semaglutide) is also highly effective:
- Average weight loss in trials: ~15% of body weight
- Targets one hormone (GLP-1)
Head-to-head trials (SURMOUNT-5) confirmed Zepbound outperformed Wegovy on average.
Which Is Easier to Get Online?
Both are accessible through telehealth, but Wegovy has more established options:
- Hims & Hers – offers compounded semaglutide (Wegovy alternative)
- Ro Body – offers both medications via telehealth
- Noom Med – provides Wegovy prescriptions online
- LifeMD – offers GLP-1 prescriptions with ongoing support
Important caveats:
- Both have had shortage issues
- Compounded versions are cheaper but less regulated
- You'll need a legitimate medical consultation
- Insurance coverage varies significantly and affects out-of-pocket cost
Bottom Line
Choose Zepbound if maximum weight loss is the priority. Choose Wegovy if you want slightly more telehealth options or better insurance coverage in your plan. Always consult a doctor to find what's right for your situation.