Verbatim response from Claude
Compounded Semaglutide vs. Wegovy: Real Differences
What's the Same
- Active ingredient (semaglutide)
- Basic mechanism of action (GLP-1 receptor agonist)
- General weight loss effect when dosed correctly
Key Real Differences
🏭 Manufacturing & Quality
- Wegovy (Novo Nordisk) is FDA-approved with strict manufacturing standards and verified purity
- Compounded versions are made by individual pharmacies — quality varies significantly by provider
💊 Formulation
- Wegovy uses a specific salt form (semaglutide sodium) that's been clinically tested
- Many compounders use semaglutide base or acetate salt — not identical, less studied
📋 Regulatory Status
- Wegovy: Full FDA approval with clinical trial data
- Compounded: NOT FDA-approved — was only legally permitted during the shortage period (which is largely ending)
💰 Cost
- Wegovy: ~$1,300+/month (insurance may help)
- Compounded: ~$200-500/month
Reputable Compounding Sources (While Legal)
If you go compounded, use 503B outsourcing facilities like those partnered with Hims/Hers, LifeMD, or Henry rather than random online pharmacies.
Bottom Line
Wegovy is the safer, proven choice if affordable. Compounded carries real quality uncertainty and increasing legal/availability risk.
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