Verbatim response from Claude
Key Blood Biomarkers for Longevity
The High-Value Ones (Strong Evidence)
Metabolic Health
- Fasting glucose & insulin - predicts diabetes and cardiovascular risk decades early
- HbA1c - 3-month glucose average; powerful mortality predictor
- Triglycerides/HDL ratio - better cardiovascular risk marker than cholesterol alone
- ApoB - superior to LDL for measuring atherogenic particles
Inflammation
- hs-CRP - high-sensitivity C-reactive protein; chronic inflammation marker
- IL-6 - interleukin-6; strongly linked to aging and disease
Other Important Ones
- DHEA-S - declines with age; associated with longevity
- IGF-1 - growth signaling; too high or low is problematic
- Homocysteine - cardiovascular and cognitive risk
- Vitamin D - deficiency linked to multiple disease risks
- Testosterone/estradiol - hormonal decline accelerates aging markers
Where to Get Tested
- Function Health - comprehensive panels, Peter Attia-associated, ~$499/year
- Inside Tracker - analyzes results with personalized recommendations
- Ulta Lab Tests - affordable à la carte ordering
- Your primary care doctor - can order most basics
Honest Caveat
Many biomarkers are associated with longevity but intervening on them doesn't always extend life - the research is still evolving.
Want specifics on any category?