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What is the best non hormonal treatment for hot flashes?

ClaudeswitchingCollected Jun 17, 2026, 13:09 UTC

Verbatim response from Claude

Best Non-Hormonal Treatments for Hot Flashes

Prescription Options (Most Effective)

  • Veozah (fezolinetant) – FDA-approved specifically for hot flashes; blocks brain receptors that trigger them. Currently the gold standard non-hormonal option.
  • Effexor (venlafaxine) – An antidepressant shown to significantly reduce hot flash frequency
  • Brisdelle (paroxetine) – The only FDA-approved SSRI specifically for hot flashes

Over-the-Counter Supplements

  • Remifemin (Black Cohosh) – One of the most studied herbal options with decent evidence
  • Relizen – A Swedish pollen extract with good clinical backing and few side effects
  • Estroven – Popular blend containing black cohosh; widely available

Lifestyle-Based

  • Embr Wave – A wristband device that uses temperature therapy to ease hot flash discomfort

Mind-Body

  • Cognitive Behavioral Therapy (CBT) – Has solid research support; apps like Menopause MindShift make it accessible

My top recommendation: Talk to your doctor about Veozah if you want the most targeted non-hormonal prescription, or try Relizen if you prefer an OTC option with good safety data.

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