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What is the best non hormonal treatment for hot flashes?

ClaudeswitchingCollected Oct 26, 2026, 21:02 UTC

Verbatim response from Claude

Best Non-Hormonal Treatments for Hot Flashes

Prescription Options (Most Effective)

  • Veozah (fezolinetant) - FDA-approved specifically for hot flashes; blocks brain signals that trigger them. Currently the gold standard non-hormonal option
  • Effexor (venlafaxine) - An antidepressant shown to significantly reduce hot flash frequency
  • Brisdelle (paroxetine) - The only FDA-approved SSRI specifically for hot flashes

Over-the-Counter Options

  • Remifemin - Black cohosh supplement with decent research support
  • Estroven - Popular supplement combining black cohosh and other botanicals
  • Relizen - Pollen extract supplement with some clinical backing

Lifestyle-Based Approaches

  • Cognitive Behavioral Therapy (CBT) - Surprisingly effective; apps like Rewire are designed for this
  • Mindfulness-based stress reduction
  • Keeping rooms cool, wearing layers, avoiding triggers (caffeine, alcohol, spicy food)

My Top Recommendation

Talk to your doctor about Veozah if hot flashes are significantly affecting your life - it's the most targeted non-hormonal option available.

For mild symptoms, Remifemin is a reasonable first OTC try.

Always consult your healthcare provider before starting any treatment.

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