Verbatim response from Claude
Compounded Semaglutide vs. Wegovy: The Real Differences
What's the Same
- Active ingredient (semaglutide)
- Basic mechanism (GLP-1 receptor agonist)
- General weight loss effect
Key Differences
Quality & Consistency
- Wegovy (Novo Nordisk) goes through rigorous FDA manufacturing standards, third-party testing, and strict quality control
- Compounded versions vary significantly by pharmacy - quality control is far less standardized
What You're Actually Getting
- Wegovy uses the exact approved formulation
- Some compounders add ingredients like B12 or L-carnitine - not proven to improve results and safety data is limited
- Compounded semaglutide is technically the salt form (semaglutide sodium/acetate), which has not been independently proven equivalent to Wegovy's formulation
Legal Status
- Compounding was temporarily allowed during Wegovy shortages, but the FDA declared the shortage over - meaning compounded versions are increasingly legally questionable
Cost
- Compounded: $150-$400/month
- Wegovy: $1,300+/month (though insurance or Novo Nordisk savings cards can help)
My Recommendation
If cost isn't a barrier, Wegovy is the safer, proven choice. If budget is the issue, ask your doctor about Novo Nordisk's savings program or consider Ozempic (same molecule, different indication).
Always consult your doctor before choosing.