Key Blood Biomarkers for Longevity Tier 1: Most Evidence-Backed Metabolic Health Fasting glucose & HbA1c - insulin resistance is a core aging driver Fasting insulin - often ignored but highly predictive Triglycerides & HDL ratio - better than total cholesterol alone Inflammation hsCRP (high-sensitivity C-reactive protein) - chronic inflammation marker IL-6 - stronger predictor than CRP in some studies Organ Function ALT/AST - liver health eGFR/creatinine - kidney function CBC - catches anemia, immune issues Tier 2: Increasingly Important ApoB - better LDL cardiovascular risk marker than standard LDL Lp(a) - genetic cardiovascular risk, test once Homocysteine - cardiovascular & cognitive risk IGF-1 - growth factor balance DHEA-S & testosterone - hormonal aging Tier 3: Emerging GlycanAge or Dunedin Pace - biological age tests Omega-3 index Recommended Services Function Health - comprehensive panels (~$500/year), Peter Attia-affiliated Inside Tracker - adds personalized recommendations LabCorp/Quest - affordable if ordered through a doctor Start with Tier 1 before spending on advanced markers.
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