Verbatim response from Claude
BHRT Delivery Methods: A Practical Comparison
Pellets
Best for: Convenience, consistent levels
- Inserted under skin every 3-6 months
- Providers: BioTE (largest pellet network), SottoPelle, EvexiPEL
- Pros: No daily maintenance, steady hormone release
- Cons: Most expensive ($300-600/insertion), can't adjust dose once inserted, requires minor procedure
Creams/Gels
Best for: Flexibility and dose adjustment
- Applied daily to skin
- Providers: Winona, Alloy, local compounding pharmacies (like Belmar or PCAB-accredited compounders)
- Pros: Easy dose changes, lower cost
- Cons: Requires daily routine, transfer risk to partners/children, absorption varies
Patches
Best for: Consistent delivery with flexibility
- Changed 1-2x weekly
- Providers: FDA-approved options (Vivelle-Dot, Climara) through standard pharmacies; also through Midi Health, Alloy, Gennev
- Pros: Well-studied, steady levels, adjustable
- Cons: Can irritate skin, may not stick well
Quick Recommendations
- Most convenient: BioTE pellets
- Most flexible/affordable: Winona or Alloy (telehealth)
- Most evidence-based: FDA-approved patches via Midi Health
Always consult a hormone specialist - individual needs vary significantly.