Verbatim response from Claude
Compounded Semaglutide vs. Wegovy: Real Differences
What's Actually the Same
- Active ingredient (semaglutide) works the same way
- Similar weight loss results when dosed correctly
- Same basic mechanism (GLP-1 receptor agonist)
Real Differences Worth Knowing
🏭 Manufacturing & Quality
- Wegovy (Novo Nordisk) undergoes rigorous FDA approval and inspection
- Compounded versions come from compounding pharmacies — quality varies significantly by pharmacy
💊 Formulation
- Wegovy uses a specific salt form (semaglutide base)
- Some compounders use semaglutide acetate or sodium — the FDA has flagged concerns about these variants
💰 Cost
- Wegovy: $1,300-$1,700/month without insurance
- Compounded: $200-$500/month typically
⚖️ Legal Status (Important Right Now)
- Compounded semaglutide was allowed during the shortage period
- FDA declared the shortage over in early 2024, meaning compounding is being phased out — check current regulations
Reputable Compounding Sources (If You Go That Route)
- Hims & Hers, Ro, LifeMD — telehealth platforms with licensed pharmacies
- Look for 503B outsourcing facilities specifically
Bottom Line
Wegovy is safer from a quality-assurance standpoint. Compounded is cheaper but carries more variability. Always use a licensed provider either way.