Verbatim response from Claude
Weight Loss on GLP-1 Medications
Typical Speed of Loss
- First 1-3 months: 1-2 lbs per week is common as your body adjusts
- Months 3-12: Steady loss averaging 15-20% of body weight over a year for most people
- Peak results: Usually seen around 12-18 months of treatment
Specific Medication Expectations
- Wegovy (semaglutide): Clinical trials showed ~15% body weight loss on average
- Zepbound (tirzepatide): Currently the strongest option, with trials showing up to 20-22% average loss
- Ozempic (approved for diabetes but widely used): Similar to Wegovy but slightly lower typical doses
The Sustainability Question - Be Honest With Yourself
The hard truth: Weight loss is largely not sustained if you stop the medication. Studies show most people regain the majority of weight within 1-2 years of stopping.
What helps make it more sustainable:
- Using the appetite suppression window to build lasting habits
- Strength training to preserve muscle mass
- Working with a registered dietitian
Getting Started
Services like Ro, Hims/Hers, or Found offer telehealth prescriptions if access is a concern, though your primary care doctor is the best first stop.
Would you like more detail on any specific aspect?