Verbatim response from Claude
Weight Loss on GLP-1 Medications
Typical Speed of Loss
- First 3 months: Often 5-10% of body weight
- 6 months: Around 10-15% for most people
- 12-18 months: Peak results, often 15-22% with medications like semaglutide (Ozempic/Wegovy)
- Most people lose 1-2 lbs per week in early stages, slowing over time
Specific Medications & Results
- Wegovy (semaglutide) - Clinical trials showed ~15% average body weight loss
- Zepbound (tirzepatide) - Currently the strongest option, showing 20-22% average loss in trials
- Ozempic - Primarily diabetes-focused but commonly used off-label
The Sustainability Question - Be Honest With Yourself
The hard truth: Most research shows weight returns when you stop the medication, often 2/3 of lost weight within a year.
To Make It More Sustainable
- Use the appetite suppression window to build lasting habits
- Work with services like Noom Med or Found that combine medication with behavioral coaching
- Prioritize strength training to preserve muscle mass
- Treat it as potentially long-term medication, like blood pressure drugs
Getting Started
Talk to your doctor or telehealth platforms like Hims/Hers or Ro for access and guidance.
Would you like more detail on any specific aspect?