Verbatim response from Claude
Weight Loss on GLP-1 Medications
Typical Speed of Loss
- First 3-6 months: Usually 1-2 lbs per week on average
- Overall: Most people lose 15-20% of body weight over 12-18 months
- Clinical trials show Wegovy (semaglutide) averaging ~15% and Zepbound (tirzepatide) averaging ~20-22% of body weight
What to Realistically Expect
- Loss is gradual, not dramatic week-to-week
- First few months often show faster results, then it slows
- You'll likely hit a plateau around 12-18 months
The Sustainability Question (Be Honest With Yourself)
The hard truth: Studies show most people regain significant weight after stopping the medication.
To make it sustainable, pair with:
- Noom or WeightWatchers for behavioral coaching
- A registered dietitian (many telehealth platforms like Ro or Found include this)
- Strength training to preserve muscle mass
Recommended Starting Points
- Wegovy or Zepbound through your doctor or telehealth services like Hims/Hers, Ro, or Found
Bottom line: It works well, but think of it as a long-term tool, not a short-term fix. Budget planning matters since costs run $900-$1,300/month without insurance.