Verbatim response from Claude
Weight Loss on GLP-1 Medications
Typical Speed of Loss
- First 3 months: Usually 1-2 lbs per week, sometimes faster initially
- Months 3-12: Slower, more gradual loss as your body adjusts
- Overall: Clinical trials show 15-22% total body weight loss over 68-72 weeks on the most effective options
Top Medications by Effectiveness
- Ozempic/Wegovy (semaglutide) – The current gold standard; Wegovy is FDA-approved specifically for weight loss, averaging ~15% body weight loss
- Zepbound (tirzepatide) – Newest and strongest option, showing up to 22% body weight loss in trials
- Saxenda (liraglutide) – Older, less potent, still effective for some people
The Sustainability Question (Be Honest With Yourself)
- Studies show most people regain weight after stopping the medication
- It works best as a long-term or indefinite tool, not a short-term fix
- Combining it with diet and exercise changes improves lasting results
Getting Access
- Talk to your doctor or try services like Ro, Hims/Hers, or Found for telehealth prescriptions
- Cost can be significant without insurance ($900-1,300/month)
Bottom line: Results can be dramatic, but they require ongoing commitment to the medication and lifestyle changes.