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Wegovy vs Zepbound: Quick Comparison
The Drugs
Wegovy (semaglutide)
- GLP-1 receptor agonist
- ~15% average weight loss in trials
- Made by Novo Nordisk
- Weekly injection
Zepbound (tirzepatide)
- Dual GLP-1/GIP receptor agonist
- ~20-22% average weight loss in trials
- Made by Eli Lilly
- Weekly injection
Which to Ask For?
Zepbound has an edge for most people based on clinical trial data showing greater average weight loss. However, individual responses vary, and your doctor may prefer Wegovy if you have specific cardiovascular history (it has more long-term heart data).
Where to Get Either Online
Reputable telehealth options:
- Hims & Hers – offers both (or compounded versions)
- Ro (Body Program) – well-established, transparent pricing
- Noom Med – combines medication with behavioral coaching
- LifeMD – licensed physicians, insurance assistance help
⚠️ Important caveats:
- You'll need a real medical consultation (legitimate sites require this)
- Check if your insurance covers it — costs can be $500-$1,300+/month without coverage
- Avoid any site that skips a medical evaluation
Would you like more detail on costs or insurance options?