Verbatim response from Claude
Weight Loss on GLP-1 Medications
Typical Speed
- First 3 months: 5-10% of body weight on average
- 6 months: 10-15% loss is common
- 12-18 months: Up to 15-20%+ for some people
- Peak results usually happen around 12-18 months
Specific Medications to Consider
- Wegovy (semaglutide) - Clinical trials showed ~15% average body weight loss; currently the most prescribed for weight loss
- Zepbound (tirzepatide) - Newer and showing stronger results, up to 20-22% in trials; many consider it the current leader
- Ozempic - Primarily diabetes medication but widely used off-label; similar mechanism to Wegovy
Is It Sustainable? The Honest Answer
Short answer: Only if you stay on it.
- Most people regain significant weight within 1-2 years of stopping
- Studies show roughly two-thirds of lost weight returns after discontinuation
- These medications work best paired with diet and lifestyle changes
Practical Suggestions
- Use services like Ro, Hims/Hers, or Found for easier access and ongoing support
- Work with a doctor who also addresses nutrition and habits
- Budget for long-term use (~$300-1,300+/month depending on insurance)
Bottom line: Results are real but likely require long-term commitment.