Verbatim response from Claude
Compounded Semaglutide vs. Wegovy: Real Differences
What's Actually the Same
- Active ingredient: Both contain semaglutide
- Mechanism: GLP-1 receptor agonist that suppresses appetite
- General effects: Weight loss, blood sugar regulation
Real Differences Worth Knowing
Wegovy (Novo Nordisk)
- FDA-approved with rigorous clinical trials backing it
- Standardized manufacturing with strict quality controls
- Consistent dosing in pre-filled auto-injectors
- Insurance coverage possible (though limited)
- Proven safety profile with years of data
Compounded Semaglutide
- Not FDA-approved - made in compounding pharmacies
- Quality varies significantly by pharmacy
- Often cheaper - sometimes 60-80% less expensive
- Was legally available during Wegovy shortage, but FDA has now flagged this as a concern
- May contain additives like B12 or L-carnitine with unproven benefits
Trusted Sources If You Go Compounded
- Hims/Hers, Ro, and LifeMD use licensed compounding pharmacies
- Look for 503B-certified compounding facilities specifically
Bottom Line Recommendation
Wegovy is the safer, more reliable choice if cost and availability aren't barriers. If cost is the issue, a 503B pharmacy through a telehealth platform is the next best option.
Always consult your doctor either way.