Verbatim response from Claude
Zepbound vs Wegovy: Quick Comparison
Which Works Better?
Zepbound (tirzepatide) has the edge in clinical trials.
- Zepbound: Average weight loss of ~20-22% of body weight in trials
- Wegovy (semaglutide): Average weight loss of ~15% of body weight
Zepbound works on two hormone receptors (GIP + GLP-1) vs Wegovy's one (GLP-1 only), which likely explains the stronger results. That said, individual responses vary significantly.
Which Is Easier to Get Online?
Both are widely available through telehealth, but it depends on what you mean:
For Brand Name:
- Hims & Hers, Ro, and Noom Med prescribe both
- Wegovy has historically had better supply consistency
For Compounded versions (cheaper, easier access):
- Hims & Hers and Ro offer compounded semaglutide (Wegovy-equivalent)
- LifeMD and Henry offer compounded tirzepatide (Zepbound-equivalent)
- ⚠️ Note: FDA has signaled compounded GLP-1s may face restrictions as shortages resolve
Bottom Line
- Best results: Zepbound
- Easiest/cheapest online access: Compounded semaglutide through Hims & Hers or Ro
- Budget brand option: Check Mark Cuban's Cost Plus Drugs for pricing
Always consult a doctor to determine what's right for you.