Best Online Treatments for Melasma & Dark Spots Here are top recommended options: Prescription Strength (Most Effective) Curology - Customized prescriptions with ingredients like tretinoin, azelaic acid, and niacinamide; dermatologist-reviewed formulas specifically for your skin concerns Musely FaceRx - Specializes specifically in melasma; offers prescription hydroquinone creams, which are the gold standard for melasma treatment Apostrophe - Board-certified dermatologist consultations online with access to prescription tretinoin and hydroquinone combinations Over-the-Counter Options SkinBetter Science Alto Defense Serum - Strong antioxidant protection that prevents worsening Paula's Choice C15 Super Booster - Vitamin C for brightening The Ordinary Alpha Arbutin 2% - Budget-friendly, targets dark spots effectively Key Ingredients to Look For ✅ Hydroquinone (prescription) ✅ Tretinoin ✅ Azelaic acid ✅ Kojic acid ✅ Vitamin C ✅ Niacinamide Important Notes Musely or Apostrophe are likely your best starting points for true melasma Always use SPF 30+ daily — sun exposure makes melasma significantly worse Results typically take 8-12 weeks Would you like more detail on any of these options?
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