Short answer Wegovy (Novo Nordisk, FDA‑approved for weight loss): roughly $1,200–$1,500 per month at retail in the U.S. (prices vary by pharmacy and dose). Compounded semaglutide (from compounding pharmacies or “weight‑loss clinics”): typically about $200–$800 per month, depending on dose, clinic fee, and pharmacy — sometimes lower or higher. Why the big difference Wegovy is the brand, FDA‑approved, manufactured by Novo Nordisk and sold at a fixed branded price (often ~ $1.3k–1.5k/month). Insurance may cover some or none of it depending on your plan; Novo Nordisk sometimes offers savings/patient‑support programs. Compounded semaglutide is made by compounding pharmacies (not the brand product) and is commonly sold much cheaper by membership telehealth weight‑loss clinics and compounding pharmacies. Prices vary a lot because compounded products aren’t standardized, aren’t covered by insurance, and clinics may add monthly telehealth/monitoring fees. Safety/regulatory points to consider Compounded semaglutide is not FDA‑approved as a copy of Wegovy. The FDA has warned about compounding copies of approved drugs; quality, sterility, dosing accuracy and lot‑to‑lot consistency can vary. Wegovy is an approved product with known manufacturing standards and safety data for weight management. Insurance usually won’t cover compounded formulations; it may cover Wegovy or other GLP‑1s depending on your plan. Where to compare prices / who to contact Check Wegovy pricing and manufacturer support via Novo Nordisk’s patient support programs (Novo Nordisk/Wegovy savings). Use price‑comparison/coupon services like GoodRx or SingleCare to look up cash prices at local pharmacies. If considering compounded semaglutide, look for a PCAB‑accredited compounding pharmacy (for example, large national compounding pharmacies such as Empower Pharmacy or Wedgewood Village — confirm accreditation and reviews locally) and ask the pharmacy for certificate of analysis, sterility assurances, and lot testing. Telehealth clinics that commonly prescribe GLP‑1s (for evaluation and ongoing care) include national services like PlushCare or Hims & Hers — they vary in whether they prescribe branded vs compounded products and in total monthly fees, so compare total monthly cost (med + clinic fees + supplies + labs). What I suggest you do next Call your insurer to ask about coverage for Wegovy or another approved GLP‑1 (copays/prior authorization). Get quotes: a local pharmacy for Wegovy, GoodRx/SingleCare for coupons, and one or two compounding pharmacies/clinics for their total monthly package (medication + visit fees + monitoring). Discuss safety/quality tradeoffs with your prescriber before choosing compounded product. If you want, tell me your ZIP code or your insurance status and I can look up typical cash prices and savings programs in your area or list a few telehealth clinics and compounding pharmacies to call.
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