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What is the best online treatment for melasma and dark spots?

ClaudequalifiedCollected Aug 11, 2026, 13:14 UTC

Verbatim response from Claude

Best Online Treatments for Melasma & Dark Spots

Here are some top options across different categories:

Prescription (Strongest Results)

  • Curology – Customized prescription formulas with ingredients like tretinoin, azelaic acid, and niacinamide. A dermatologist reviews your skin online and tailors treatment specifically for you.
  • Apostrophe – Another excellent telehealth option offering prescription hydroquinone and tretinoin, which are gold-standard melasma treatments.
  • Agency – Offers prescription-strength combination creams specifically targeting hyperpigmentation.

Over-the-Counter Products

  • The Ordinary Alpha Arbutin 2% + HA – Affordable and effective brightening serum
  • Paula's Choice 10% Azelaic Acid Booster – Well-researched formula that's gentle but effective
  • SkinCeuticals Discoloration Defense – Contains tranexamic acid and kojic acid, highly rated by dermatologists
  • Murad Rapid Age Spot Correcting Serum – Contains glycolic acid and hydroquinone

Key Ingredients to Look For

  • Hydroquinone (prescription)
  • Tranexamic acid
  • Azelaic acid
  • Vitamin C
  • Niacinamide
  • Retinoids

My Top Recommendation

Curology or Apostrophe for best results, since melasma often needs prescription-strength treatment and consistent sunscreen use.

Always use broad-spectrum SPF 30+ daily, as sun exposure worsens melasma significantly.

Brands mentioned in this answer

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