Best Online Treatments for Melasma & Dark Spots Here are some top recommended options: Prescription-Strength (Most Effective) Curology – Personalized prescriptions with ingredients like tretinoin, azelaic acid, and niacinamide. A dermatology provider customizes your formula specifically for hyperpigmentation. Apostrophe – Online dermatology service that can prescribe hydroquinone (the gold standard for melasma) and tretinoin combinations. Hims/Hers – Offers prescription topicals for dark spots through a quick online consultation. Over-the-Counter Products Murad Rapid Age Spot Correcting Serum – Contains glycolic acid and vitamin C, well-reviewed for dark spots. Paula's Choice 10% Azelaic Acid Booster – Azelaic acid is clinically proven for melasma. The Ordinary Alpha Arbutin 2% + HA – Budget-friendly and effective brightening serum. SkinCeuticals Discoloration Defense – Dermatologist-recommended with tranexamic acid. Key Ingredients to Look For Hydroquinone (prescription) Tretinoin Tranexamic acid Azelaic acid Vitamin C Niacinamide My Top Pick Apostrophe or Curology for prescription-strength treatment, since melasma especially responds best to professional-grade ingredients. Always pair any treatment with SPF 30+ sunscreen daily ☀️
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