Specific compounded GLP‑1 providers that use licensed U.S. pharmacies include Empower Pharmacy, OrderlyMeds, Henry Meds (via Adonis Health Inc.), and Fridays (though Fridays does not name all partners publicly). Here’s a breakdown of who they are and how they operate: Provider Licensed U.S. Pharmacy Partners Notes Empower Pharmacy Operates its own 503A PCAB‑accredited compounding pharmacy (licensed in multiple states) Ships nationwide, including Puerto Rico; offers compounded semaglutide and tirzepatide [1] OrderlyMeds Works exclusively with U.S.-based licensed pharmacies: SmartPharmaRx, Casa, PerfectRx/PerfectionRx All pharmacies are state‑licensed 503A facilities; provides cold‑chain shipping [6] Henry Meds (Adonis Health Inc.) Uses 503A and 503B compounding pharmacies (specific partners not named on marketing pages) One of the most transparent providers; mentions its medical group (Colchis Medical Services PC) [3] Fridays Uses 503A and 503B certified compounding pharmacies; customer reviews mention Beaker Pharmacy as a partner Does not name all partners publicly; patients can ask support which pharmacy will fill their prescription [3] Important regulatory context Compounded GLP‑1s (semaglutide, tirzepatide) are not FDA‑approved and are only legally allowed when the commercially available version is in a verified shortage [2]. As of May 2025, most grace periods for compounded semaglutide and tirzepatide injections have ended; shortages are now resolved, so regular compounding of “essentially copies” of FDA‑approved drugs is no longer permitted except for specific medical needs (e.g., non‑standard doses or forms) [5]. Compounded semaglutide can currently only come from 503A pharmacies, and a single 503A pharmacy may fill no more than four prescriptions per patient per calendar month [3]. If you’re considering a compounded GLP‑1, confirm with the provider: Whether they have a specific medical justification for compounding (e.g., unique dose, allergen removal). Which licensed U.S. pharmacy will fill your prescription. Whether they comply with the current 4‑prescription/month limit for 503A compounding of semaglutide. For the most reliable option with a fully licensed U.S. pharmacy under your control, Empower Pharmacy and OrderlyMeds are strong choices because they explicitly name or operate their own licensed facilities and emphasize state compliance.
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