PerfectRx

Based on the provided search results, the following compounded GLP-1 providers explicitly state that they use licensed US pharmacies (specifically citing 503A or 503B facilities based in the United States): OrderlyMeds Explicitly states they work "exclusively with pharmacies based in the United States." Lists specific US partners: SmartPharmaRx, Casa, and PerfectRx/PerfectionRx. Describes itself as a "100% online platform that connects patients to licensed healthcare professionals in all 50 states." Empower Pharmacy States their medications are made at a "503A PCAB-Accredited compounding pharmacy" (a US standard). Confirms they are licensed to "ship nationwide, including Puerto Rico," indicating a US-based operation. Henry Meds (and its partner Adonis Health Inc.) Described as "upfront" about using both 503A and 503B compounding pharmacies. Cites partner pharmacies: Belmar Pharmacy, Strive Pharmacy, Epiq Scripts, and Casa Pharma Rx (all US-based entities). Fridays Weight Loss Program (joinfridays.com) States they "deliver from 503A and 503B certified compounding pharmacies." While they do not name all partners on marketing pages, they reference Beaker Pharmacy as a fulfillment partner. The FDA clarification mentioned in the text notes that compounded semaglutide must legally come from 503A pharmacies (US standard), which Fridays claims to use. Schaffner Pharmacy Explicitly states their products are made by "FDA certified 503B compounding pharmacies," which are US-regulated facilities. Important Regulatory Context (from results): FDA Shortage Status: As of May 2025, the FDA shortages for semaglutide and tirzepatide injections have been resolved. Consequently, pharmacies are generally no longer allowed to regularly compound "essentially copies" of commercially available GLP-1s. Current Availability: Compounded versions are now largely phased out and should only be used for specific medical needs that commercial products cannot meet (e.g., non-standard doses or removing allergens). 503A vs. 503B: 503A pharmacies are traditional compounding pharmacies licensed by state boards for individual patients, while 503B facilities are outsourcing facilities regulated by the FDA. Both are US-licensed entities. Summary: The providers most clearly identified as using licensed US pharmacies are OrderlyMeds, Empower Pharmacy, Henry Meds, Fridays, and Schaffner Pharmacy. OrderlyMeds is the most explicit about its exclusive use of US-based partners.

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