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What is the best non hormonal treatment for hot flashes?

ClaudeswitchingCollected Oct 16, 2026, 11:31 UTC

Verbatim response from Claude

Best Non-Hormonal Treatments for Hot Flashes

Prescription Options (Most Effective)

  • Veozah (fezolinetant) - FDA-approved specifically for hot flashes; blocks brain receptors that trigger them. Currently the gold standard non-hormonal option
  • Effexor (venlafaxine) - An antidepressant shown to significantly reduce hot flash frequency
  • Brisdelle (paroxetine) - The only SSRI FDA-approved for hot flashes

Over-the-Counter Supplements

  • Remifemin (black cohosh) - One of the most studied herbal options with decent evidence
  • Estroven - Popular menopause supplement combining multiple ingredients
  • Equelle (S-equol) - Derived from soy, has good clinical research behind it

Lifestyle Approaches

  • Cooling products: Embr Wave wristband uses temperature therapy
  • Bedding: Chilipad or BedJet cooling systems for night sweats
  • Clothing: Become or Cool-jams moisture-wicking sleepwear

Mind-Body

  • Cognitive Behavioral Therapy (CBT) - Strong evidence for reducing hot flash distress
  • Mindfulness-Based Stress Reduction (MBSR) programs

I'd recommend speaking with your doctor first, as Veozah or a low-dose antidepressant typically offers the most reliable relief. Would you like more detail on any of these?

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